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Article

High-resolution analysis of intrahost genetic diversity in dengue virus serotype 1 infection identifies mixed infections.

Journal of virology - 1 Jan 2012

Thai Khoa T D, Henn Matthew R, Zody Michael C, Tricou Vianney, Nguyet Nguyen Minh, Charlebois Patrick, Lennon Niall J, Green Lisa, de Vries Peter J, Hien Tran Tinh, Farrar Jeremy, van Doorn H Rogier, de Jong Menno D, Birren Bruce W, Holmes Edward C, Simmons Cameron P

Abstract excerpt

Little is known about the rate at which genetic variation is generated within intrahost populations of dengue virus (DENV) and what implications this diversity has for dengue pathogenesis, disease severity, and host immunity. Previous studies of intrahost DENV variation have used a low frequency of sampling and/or experimental methods that do not fully account for errors generated through amplification and...

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Identifiers

PMID: 22090119
DOI: 10.1128/JVI.05985-11
PMCID: PMC3255838

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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