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Article

Feasibility of using 454 pyrosequencing for studying quasispecies of the whole dengue viral genome.

BMC genomics - 1 Jan 2012

Chin-inmanu Kwanrutai, Suttitheptumrong Aroonroong, Sangsrakru Duangjai, Tangphatsornruang Sithichoke, Tragoonrung Somvong, Malasit Prida, Tungpradabkul Sumalee, Suriyaphol Prapat

Abstract excerpt

BACKGROUND: Dengue is the world's most common mosquito-borne viral disease. Poor proofreading by RNA polymerase during its replication results in the accumulation of mutations in its genome. This leads to a diversity of genotypes in the viral population termed quasispecies. Quasispecies play an important role in disease severity. The study of quasispecies in dengue has been hindered because of the requirement for...

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Identifiers

PMID: 23281804
DOI: 10.1186/1471-2164-13-S7-S7
PMCID: PMC3521222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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