Article
Widespread intra-serotype recombination in natural populations of dengue virus.
Proceedings of the National Academy of Sciences of the United States of America - 22 Jun 1999
Worobey M, Rambaut A, Holmes E C
Abstract excerpt
Diversity analysis of 71 published dengue virus gene sequences revealed several strains that appeared to be mosaics comprising gene regions with conflicting evolutionary histories. Subsequent maximum likelihood breakpoint estimation identified seven recombinants, including members of three of the four dengue virus serotypes, with breakpoints in the premembrane/membrane gene, the envelope gene, and at the junction...
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