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Article

TNF rs1799964 as a Predictive Factor of Acute Toxicities in Chinese Rectal Cancer Patients Treated With Chemoradiotherapy.

Medicine - 1 Nov 2015

Zhang Hui, Wang Mengyun, Shi Tingyan, Shen Lijun, Liang Liping, Deng Yun, Li Guichao, Zhu Ji, Wu Yongxin, Fan Ming, Deng Weijuan, Wei Qingyi, Zhang Zhen

Abstract excerpt

Acute toxicity is the main dose-limiting factor in the chemoradiotherapy of rectal cancer patients and depends on several pro-inflammatory factors, including interleukin-1 (IL-1), IL-6, and tumor necrosis factor-alpha (TNF-α). It is unknown whether genetic factors, such as single-nucleotide polymorphisms (SNPs) in the IL-1, IL-6, and TNF genes, are also associated with acute toxicity in the process.We genotyped 5...

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Identifiers

PMID: 26559268
DOI: 10.1097/MD.0000000000001955
PMCID: PMC4912262

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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