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Article

Single Nucleotide Polymorphism TGFβ1 R25P Correlates with Acute Toxicity during Neoadjuvant Chemoradiotherapy in Rectal Cancer Patients.

International journal of radiation oncology, biology, physics - 1 Apr 2017

Smith J Joshua, Wasserman Isaac, Milgrom Sarah A, Chow Oliver S, Chen Chin-Tung, Patil Sujata, Goodman Karyn A, Garcia-Aguilar Julio

Abstract excerpt

PURPOSE: To validate the finding of an association between single nucleotide polymorphisms (SNPs) and toxicity during chemoradiotherapy (CRT) in rectal cancer patients, in an independent population. METHODS AND MATERIALS: The cohort consisted of 165 patients who received CRT for rectal cancer from 2006 to 2012. Prospectively recorded toxicity information, graded according to the Common Terminology Criteria for...

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Identifiers

PMID: 28333014
DOI: 10.1016/j.ijrobp.2016.12.015
PMCID: PMC5389377

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XRCC1

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