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Colorectal cancer severity and survival in correlation with tumour necrosis factor-alpha

3 Sept 2014

Abstract excerpt

Colorectal cancer (CRC) development is strongly associated with innate immune mechanisms and intestinal inflammation. The aim of the study was to investigate the pre-operative serum levels of TNF-α and its correlation with cancer progression and survival in CRC patients taking into account the genotype of –308G/A promoter polymorphism in TNF-α gene (rs1800629). TNF-α –308G/A genotypes of 119 CRC cases and 177 no...

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PMID: 26019577
DOI: 10.1080/13102818.2014.965047

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