Article
TNF-α -308 A allele is associated with an increased risk of distant metastasis in rectal cancer patients from Southwestern China.
PloS one - 1 Jan 2017
Li Zhen, Li Shu-An, Sun Ya, Liu Yu, Li Wen-Liang, Yang Li, Duan Yong, Li Jingyu, Guo Hao, Zou Tian-Ning, Li Yunlong, Wang Kun-Hua
Abstract excerpt
Tumor necrosis factor-α (TNF-α), an important factor in systematic inflammation, is reportedly involved in several cancer types. The TNF-α -308 G>A (rs1800629) polymorphism in the promoter region influences TNF-α production. The association between TNF-α -308 G>A polymorphism and colorectal cancer (CRC) is not fully understood, especially the connections between TNF-α -308 G>A polymorphism and clinical features...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.