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IL1B rs1143634 Genotype Identifies Differential Cancer-Specific Survival by Neoadjuvant Strategy in Locally Advanced Rectal Cancer: A Prospective Randomized Trial

2026-05-29

Abstract excerpt

<h4>Background: </h4> Locally advanced rectal cancer (LARC) treatment selection between neoadjuvant intensified chemotherapy (NIC) and standard chemoradiotherapy (CRT) lacks validated predictive biomarkers. Interleukin-1β (IL1B) polymorphisms modulate IL-1β expression and may influence treatment-specific outcomes through tumor microenvironment remodeling. <h4>Methods:</h4> In this prospective, single-center, rando...

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Literature Corpus work
3a3ef71f-2261-5b55-aa76-a1386bf2c09d
DOI
10.20944/preprints202605.2004.v1
Open publication

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IL1B rs1143634 Genotype Identifies Differential Cancer-Specific Survival by Neoadjuvant Strategy in Locally Advanced Rectal Cancer: A Prospective Randomized TrialDOI 10.20944/preprints202605.2004.v1
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