Article
[Associations of genetic variations in pyroptosis related genes with acute adverse events in postoperative rectal cancer patients receiving concurrent chemoradiotherapy].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 23 Feb 2023
Chen H X, Ren N X, Yang J, Chen J N, Lu Q X, Feng Y R, Huang Y, Yin L L, Lin D X, Li Y X, Jin J, Tan W
Abstract excerpt
Objective: This study aims to investigate the associations between genetic variations of pyroptosis pathway related key genes and adverse events (AEs) of postoperative chemoradiotherapy (CRT) in patients with rectal cancer. Methods: DNA was extracted from the peripheral blood which was collected from 347 patients before CRT. Sequenom MassARRAY was used to detect the genotypes of 43 haplotype-tagging single...
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