Article
Association of TGF-β1 and XPD polymorphisms with severe acute radiation-induced esophageal toxicity in locally advanced lung cancer patients treated with radiotherapy.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Oct 2010
Zhang Li, Yang Ming, Bi Nan, Ji Wei, Wu Chen, Tan Wen, Zhao Lujun, Yu Dianke, Lin Dongxin, Wang Luhua
Abstract excerpt
PURPOSE: Radiation-induced esophageal toxicity (RIET) is a dose-limiting toxicity in lung cancer patients receiving radiotherapy. Accumulating evidence indicates that DNA repair and the cytokine pathways play essential roles in radiation-induced diseases. Genetic polymorphisms of genes in these p...
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