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Detecting Arbitrary DNA Mutations Using Graphene Oxide and Ethidium Bromide.

Analytical chemistry - 15 Dec 2015

Huang Jiahao, Wang Zhenyu, Kim Jang-Kyo, Su Xuefen, Li Zhigang

Abstract excerpt

We propose a simple and fast method for detecting arbitrary DNA mutations. Single-stranded DNA probes labeled with fluorescein amidite (FAM-ssDNA), ethidium bromide (EB), and graphene oxide (GO) are employed in the sensing system. The detection is achieved in two steps. In the first step, the sensing system contains FAM-ssDNA probes and EB molecules. It exhibits different fluorescence emissions in the presence of...

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PMID: 26559174
DOI: 10.1021/acs.analchem.5b03369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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