Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A simple PCR-based fluorometric system for detection of mutant fusion DNAs using a quencher-free fluorescent DNA probe and graphene oxide.

Chemical communications (Cambridge, England) - 25 Apr 2015

Roh Kyoungmin, Kim Dong-Min, Lee Eun Hee, Kim Hyoseon, Park Hyung Soon, Jang Ja-Hyun, Hwang Sang-Hyun, Kim Dong-Eun

Abstract excerpt

We propose a facile fluorometric system for detection of gene mutations using graphene oxide (GO). A fluorescent probe DNA anneals to a specific mutant gene and is degraded by the 5'→ 3' exonuclease activity of Taq polymerase during PCR, and the released fluorophore retains fluorescence after add...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Probes
Share to Fluorescent Dyes
Share to Fluorometry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fusion Proteins, bcr-abl

Share to Mutation

Share to Oxides

Share to Polymerase Chain Reaction

Share to Taq Polymerase

Source

Identifiers

PMID: 25797656
DOI: 10.1039/c5cc00263j

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25797656-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A simple PCR-based fluorometric system for detection of mutant fusion DNAs using a quencher-free fluorescent DNA probe and graphene oxide.PMID 25797656Read ↗

Detecting Arbitrary DNA Mutations Using Graphene Oxide and Ethidium Bromide.Semantic proximity Read ↗

A graphene-based platform for fluorescent detection of SNPs.Semantic proximity Read ↗

Fluorescence-based detection of single-nucleotide changes in RNA using graphene oxide and DNAzyme.Semantic proximity Read ↗

Improving the sensitivity and selectivity of a DNA probe using graphene oxide-protected and T7 exonuclease-assisted signal amplification.Semantic proximity Read ↗

Fluorometric detection of EGFR exon 19 deletion mutation in lung cancer cells using graphene oxide.Semantic proximity Read ↗

DNA single-base mismatch study using graphene oxide nanosheets-based fluorometric biosensors.Semantic proximity Read ↗

Label-Free Detection of DNA Mutations by Nanopore Analysis.Semantic proximity Read ↗

Discrimination of single-point mutations in unamplified genomic DNA via Cas9 immobilized on a graphene field-effect transistor.Semantic proximity Read ↗

Graphene oxide and self-avoiding molecular recognition systems-assisted recombinase polymerase amplification coupled with lateral flow bioassay for nucleic acid detection.Semantic proximity Read ↗

A simple and ultrasensitive fluorescence assay for single-nucleotide polymorphism.Semantic proximity Read ↗

Single-base mismatch discrimination by T7 exonuclease with target cyclic amplification detection.Semantic proximity Read ↗

Colorimetric detection of single-nucleotide polymorphisms with a real-time PCR-like sensitivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.