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Article

Interaction between cytochrome P450 2A6 and Catechol-O-Methyltransferase genes and their association with smoking risk in young men.

Behavioral and brain functions : BBF - 4 May 2017

Ou Wei-Chih, Huang Yi-Chin, Huang Chih-Ling, Lin Min-Hsuan, Chen Yi-Chun, Chen Yi-Ju, Liu Chen-Nu, Chen Mei-Chih, Huang Ching-Shan, Chen Pei-Lain

Abstract excerpt

BACKGROUND: Although some effects of gene-gene interactions on nicotine-dopamine metabolism for smoking behavior have been reported, polymorphisms of cytochrome P450 (CYP) 2A6 and catechol-O-methyltransferase (COMT) have not been studied together to determine their effects on smokers. The aim of this study was to investigate the effects of the interaction between the CYP 2A6 and COMT genes on smoking behavior in...

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Identifiers

PMID: 28472995
DOI: 10.1186/s12993-017-0127-2
PMCID: PMC5418756

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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