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Article

The effects of the apoE4 genotype on the developing mouse retina.

Experimental eye research - 1 Apr 2016

Maharshak Idit, Salomon-Zimri Shiran, Antes Ran, Liraz Ori, Nisgav Yael, Livnat Tami, Weinberger Dov, Colton Carol A, Solomon Arieh S, Michaelson Daniel M

Abstract excerpt

Apolipoprotein E4 (apoE4), the most prevalent genetic risk factor for Alzheimer's disease (AD), is associated with neuronal and vascular impairments. The retina, which is as an extension of the central nervous system (CNS), is a particularly suitable model for studying developmental and functional aspects of the neuronal and vascular systems. This study investigates the apoE4-dependent developmental effects on...

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Source

Identifiers

PMID: 26554939
DOI: 10.1016/j.exer.2015.11.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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