Article

Longitudinal investigation of spatial memory and retinal parameters in a 5xFAD model of Alzheimer’s disease reveals differences dependent on genotype and sex

2025-05-28

Abstract excerpt

<h4>Significance</h4> The retinal phenotype of Alzheimer’s disease (AD) is poorly understood. The connection between spatial memory and retinal phenotype is poorly investigated. Additionally, the influence of sex on the disease in mouse models is not sufficiently clear and requires further investigation. <h4>Aim</h4> To investigate the retina and spatial memory of 5xFAD mouse models of AD by measuring retinal an...

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Literature Corpus work: 9be1d928-84cb-504a-b190-65393735ab79
DOI: 10.1101/2025.05.23.655771

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