Article
Germline copy number variation analysis in Finnish families with hereditary prostate cancer.
The Prostate - 15 Feb 2016
Laitinen Virpi H, Akinrinade Oyediran, Rantapero Tommi, Tammela Teuvo L J, Wahlfors Tiina, Schleutker Johanna
Abstract excerpt
BACKGROUND: The inherited factors that predispose individuals to prostate cancer (PrCa) remain largely unknown. The aim of this study was to identify germline copy number variants (CNVs) in Finnish individuals that could contribute to an increased PrCa risk. METHODS: Genome-wide CNV screening was performed by analyzing single nucleotide polymorphisms from 105 PrCa patients and 37 unaffected relatives,...
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