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Article

Genetic changes in familial prostate cancer by comparative genomic hybridization.

The Prostate - 15 Feb 2001

Rökman A, Koivisto P A, Matikainen M P, Kuukasjärvi T, Poutiainen M, Helin H J, Karhu R, Kallioniemi O P, Schleutker J

Abstract excerpt

BACKGROUND: Germline mutations in recessive cancer predisposition genes are uncovered by somatic genetic deletions during tumor development. Analysis of genetic changes in tumor tissues from patients with an inherited predisposition may therefore highlight regions of the genome containing susceptibility or modifier genes. Our aim was to characterize genetic changes in familial prostate cancer METHODS: Twenty-one...

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PMID: 11170152
DOI: 10.1002/1097-0045(20010215)46:3<233::aid-pros1028>3.0.co;2-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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