Article
Genome-wide linkage scan for prostate cancer susceptibility in Finland: evidence for a novel locus on 2q37.3 and confirmation of signal on 17q21-q22.
International journal of cancer - 15 Nov 2011
Cropp Cheryl D, Simpson Claire L, Wahlfors Tiina, Ha Nati, George Asha, Jones MaryPat S, Harper Ursula, Ponciano-Jackson Damaris, Green Tiffany A, Tammela Teuvo L J, Bailey-Wilson Joan, Schleutker Johanna
Abstract excerpt
Genome-wide linkage studies have been used to localize rare and highly penetrant prostate cancer (PRCA) susceptibility genes. Linkage studies performed in different ethnic backgrounds and populations have been somewhat disparate, resulting in multiple, often irreproducible signals because of genetic heterogeneity and high sporadic background of the disease. Our first genome-wide linkage study and subsequent...
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