Article
Gene-environment interaction of genome-wide association study-identified susceptibility loci and meat-cooking mutagens in the etiology of renal cell carcinoma.
Cancer - 1 Jan 2016
Melkonian Stephanie C, Daniel Carrie R, Ye Yuanqing, Tannir Nizar M, Karam Jose A, Matin Surena F, Wood Christopher G, Wu Xifeng
Abstract excerpt
BACKGROUND: Meat-cooking mutagens may be associated with renal cell carcinoma (RCC) risk. In the current study, the authors examined associations between meat-cooking mutagens, genetic susceptibility variants, and risk of RCC. METHODS: The authors used 659 newly diagnosed RCC cases and 699 healthy controls to investigate the association between dietary intake of meat-cooking mutagens and RCC. They examined...
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