Article
Precision medicine from the renal cancer genome.
Nature reviews. Nephrology - 1 Nov 2016
Riazalhosseini Yasser, Lathrop Mark
Abstract excerpt
Genomics is revolutionizing our understanding of the molecular basis of renal cell carcinoma (RCC). The advent of unbiased genome-wide association studies has led to the discovery of previously unrecognized genetic predisposing factors that impact an individual's risk of developing RCC. Moreover, large-scale investigations of somatic alterations of the genomic and transcriptomic landscapes in tumours using...
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