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Article

Genotype-guided therapy improves initial acenocoumarol dosing. Results from a prospective randomised study.

Thrombosis and haemostasis - 1 Jan 2016

Cerezo-Manchado Juan Jose, Roldán Vanessa, Corral Javier, Rosafalco Mario, Antón Ana Isabel, Padilla Jose, Vicente Vicente, González-Conejero Rocio

Abstract excerpt

A few trials so far have evaluated the effectiveness of algorithms designed to calculate doses in oral anticoagulant therapy, with negative or contradictory results. We compared a genotype-guided algorithm vs physician management for the initiation of acenocoumarol. In a two-arm, prospective, randomised study with patients with atrial fibrillation who started therapy, the first dose was administered to all...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26538428
DOI: 10.1160/TH14-09-0814

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Genotype-guided therapy improves initial acenocoumarol dosing. Results from a prospective randomised study.PMID 26538428Read ↗

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