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Article

Genotype-Guided Dosing of Coumarin Anticoagulants: A Meta-analysis of Randomized Controlled Trials.

Journal of cardiovascular pharmacology and therapeutics - 1 Jul 2015

Tang Tao, Liu Jie, Zuo Keqiang, Cheng Jie, Chen Linyin, Lu Chenhui, Han Shilong, Xu Jichong, Jia Zhongzhi, Ye Meng, Pei Erli, Zhang Xiaoping, Li Maoquan

Abstract excerpt

BACKGROUND: Coumarin anticoagulants (acenocoumarol, phenprocoumon, and warfarin) are generally used for the prevention of stroke in patients with atrial fibrillation or for the therapy and prevention of venous thromboembolism. However, the safe use of coumarin anticoagulants is restricted by a narrow therapeutic window and large interindividual dosing variations. Some studies found that the effectiveness and...

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Identifiers

PMID: 25575537
DOI: 10.1177/1074248414565666

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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