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Article

Prediction of stable acenocoumarol dose by a pharmacogenetic algorithm.

Pharmacogenetics and genomics - 1 Oct 2014

Jiménez-Varo Enrique, Cañadas-Garre Marisa, Gutiérrez-Pimentel María J, Calleja-Hernández Miguel A

Abstract excerpt

AIM: To develop an acenocoumarol (ACN) dosing algorithm for patients with atrial fibrillation or venous thromboembolism, considering the influence on the stable ACN dose of clinical factors and gene polymorphisms, including CYP2C9*2/*3, VKORC1, CYP4F2*3, ABCB1, APOE, CYP2C19*2/*17, and GGCX. METHODS AND RESULTS: A retrospective observational study was carried out to obtain clinical and pharmacogenetic dose...

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Source

Identifiers

PMID: 25089947
DOI: 10.1097/FPC.0000000000000082

Genes

APOE
VKORC1
ABCB1
GGCX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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