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Article

Colorectal Cancers with the Uncommon Findings of KRAS Mutation and Microsatellite Instability.

Cytogenetic and genome research - 1 Jan 2015

Zauber Peter, Marotta Stephen, Sabbath-Solitare Marlene

Abstract excerpt

Sporadic colorectal cancers with microsatellite instability (MSI) frequently contain a mutation of the BRAF gene. Additionally, it has been shown that BRAF mutations in colorectal cancers are mutually exclusive of KRAS mutation. We evaluated 14 cases of colorectal cancer with MSI that were BRAF wild type but demonstrated a KRAS mutation. The codon 12/13 region in exon 2 of the KRAS oncogene and the codon 600...

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Source

Identifiers

PMID: 26523369
DOI: 10.1159/000441086

Genes

KRAS
BRAF
MLH1
MSH2
MGMT
MSH6
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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