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Article

Role of the BRAF mutations in the microsatellite instability genetic pathway in sporadic colorectal cancer.

Annals of surgical oncology - 1 Mar 2007

Maestro M L, Vidaurreta M, Sanz-Casla M T, Rafael S, Veganzones S, Martínez A, Aguilera C, Herranz M D, Cerdán J, Arroyo M

Abstract excerpt

BACKGROUND AND AIMS: Between 10 and 15% of all cases of colorectal cancer are the result of microsatellite instability (MSI) in the genetic pathway due to an alteration in the DNA repair genes. Tumors with high MSI are characterized by a better prognosis. The BRAF oncogene has been linked to the MSI pathway in tumorogenesis. The objective of this study was to determine whether alterations in BRAF are related to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17195912
DOI: 10.1245/s10434-006-9111-z

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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