Article
An association of AKT1 gene polymorphism with antidepressant treatment response.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Apr 2016
Losenkov Innokentiy S, Vyalova Natalya M, Simutkin German G, Bokhan Nikolay A, Ivanova Svetlana A
Abstract excerpt
OBJECTIVES: Nowadays it is considered that protein kinase Akt1 could be involved in pathogenesis of affective disorders. We have examined whether AKT1 gene polymorphisms are associated with antidepressant treatment response. METHODS: The study included 106 Caucasian patients with depressive disorders from Siberia and 103 healthy control donors. The frequencies of single nucleotide polymorphisms rs1130214 and...
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