Evaluation of the role of MAPK1 and CREB1 polymorphisms on treatment resistance, response and remission in mood disorder patients.

doi:10.1016/j.pnpbp.2013.03.005

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Article

Evaluation of the role of MAPK1 and CREB1 polymorphisms on treatment resistance, response and remission in mood disorder patients.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Jul 2013

Calati Raffaella, Crisafulli Concetta, Balestri Martina, Serretti Alessandro, Spina Edoardo, Calabrò Marco, Sidoti Antonina, Albani Diego, Massat Isabelle, Höfer Peter, Amital Daniela, Juven-Wetzler Alzbeta, Kasper Siegfried, Zohar Joseph, Souery Daniel, Montgomery Stuart, Mendlewicz Julien

Abstract excerpt

Treatment resistant depression (TRD) is a significant clinical and public health problem. Among others, neuroplasticity and inflammatory pathways seem to play a crucial role in the pathomechanisms of antidepressant efficacy. The primary aim of this study was to investigate whether a set of single nucleotide polymorphisms (SNPs) within two genes implicated in neuroplasticity and inflammatory processes (the mitogen...

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Identifiers

PMID: 23537502
DOI: 10.1016/j.pnpbp.2013.03.005

Genes

MAPK1
TRD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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