Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CHL1, ITGB3 and SLC6A4 gene expression and antidepressant drug response: results from the Munich Antidepressant Response Signature (MARS) study.

Pharmacogenomics - 1 Jan 2015

Probst-Schendzielorz Kristina, Scholl Catharina, Efimkina Olga, Ersfeld Eva, Viviani Roberto, Serretti Alessandro, Fabbri Chiara, Gurwitz David, Lucae Susanne, Ising Marcus, Paul Anna Maria, Lehmann Marie-Louise, Steffens Michael, Crisafulli Concetta, Calabrò Marco, Holsboer Florian, Stingl Julia

Abstract excerpt

AIM: The identification of antidepressant drugs (ADs) response biomarkers in depression is of high clinical importance. We explored CHL1 and ITGB3 expression as tentative response biomarkers. MATERIALS & METHODS: In vitro sensitivity to ADs, as well as gene expression and genetic variants of the candidate genes CHL1, ITGB3 and SLC6A4 were measured in lymphoblastoid cell lines (LCLs) of 58 depressed patients....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antidepressive Agents
Share to Biomarkers, Pharmacological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Adhesion Molecules

Share to Depressive Disorder, Major

Share to Germany

Share to Integrin beta3

Share to Serotonin Plasma Membrane Transport Proteins

Share to Switzerland

Source

Identifiers

PMID: 25943212
DOI: 10.2217/pgs.15.31

Genes

CHL1
ITGB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CHL1, ITGB3 and SLC6A4 gene expression and antidepressant drug response: results from the Munich Antidepressant Response Signature (MARS) study.PMID 25943212Read ↗

Genome-wide Expression Profiling of Human Lymphoblastoid Cell Lines Identifies CHL1 as a Putative SSRI Antidepressant Response BiomarkerSemantic proximity Read ↗

Neuronal cell adhesion genes and antidepressant response in three independent samples.Semantic proximity Read ↗

Treatment-emergent and trajectory-based peripheral gene expression markers of antidepressant responseSemantic proximity Read ↗

Cohort Profile: Investigating Antidepressant Response within Generation ScotlandSemantic proximity Read ↗

The MAKE Biomarker Discovery for Enhancing anTidepressant Treatment Effect and Response Study: Design and MethodologySemantic proximity Read ↗

Cohort Profile: Investigating Antidepressant Response within Generation ScotlandSemantic proximity Read ↗

Individualized Treatment Strategy for Depressive Disorder.Semantic proximity Read ↗

Pharmacogenetic association of bi- and triallelic polymorphisms of SLC6A4 with antidepressant response in major depressive disorder.Semantic proximity Read ↗

Genome-wide association studies of antidepressant outcome: a brief review.Semantic proximity Read ↗

ABCB6, ABCB1 and ABCG1 genetic polymorphisms and antidepressant response of SSRIs in Chinese depressive patients.Semantic proximity Read ↗

From Pharmacogenetics to Pharmacogenomics: The Way toward the Personalization of Antidepressant TreatmentSemantic proximity Read ↗

Epigenetic Signatures in Antidepressant Treatment Response: a Methylome-wide Association Study in the EMC TrialSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.