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Article

[Evaluation of the Association between Lithium Treatment and GSK3β Polymorphism in Bipolar Disorder Patients].

Turk psikiyatri dergisi = Turkish journal of psychiatry - 1 Jan 2018

Altınbaş Kürşat, Yeşilbaş Dilek, İnce Bahri, Cansız Alparslan, Sılan Fatma, Özdemir Öztürk, Gülöksüz Sinan

Abstract excerpt

OBJECTIVE: There is a lack of evidence regarding clinical predictors for the treatment response to lithium, which is the main stay treatment option for bipolar disorder. Studies that examined the mechanistic action of lithium revealed that glycogen synthase kinase 3β (GSK-3β) enzymeinhibition was important in regard to treatment responses. Based on this background, we aimed to investigate the association between...

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PMID: 30215834

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