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Article

Genetic variant of AKT1 and AKTIP associated with late-onset depression in a Brazilian population.

International journal of geriatric psychiatry - 1 Apr 2014

Pereira Patricia Araújo, Bicalho Maria Aparecida Camargos, de Moraes Edgar Nunes, Malloy-Diniz Leandro, Bozzi Isadora Cristine Reis Sguizzato, Nicolato Rodrigo, Valadão Daniela Rosa, Miranda Debora Marques, Romano-Silva Marco Aurélio

Abstract excerpt

OBJECTIVES: Examine the association between polymorphisms in the AKT1 and AKTIP genes and late-onset depression (LOD). Major depressive disorder is one of the most prevalent neuropsychiatric diseases. LOD is a disorder that starts after 65 years old. AKT1 is a downstream enzyme that has been implicated in the pathogenesis of neurotransmitter-related disorders, such as depression. The identification of a novel...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24022875
DOI: 10.1002/gps.4018

Genes

AKT1
AKTIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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