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Article

microRNA-145 promotes differentiation in human urothelial carcinoma through down-regulation of syndecan-1

29 Oct 2015

Abstract excerpt

BACKGROUND: A new molecular marker of carcinoma in the urinary bladder is needed as a diagnostic tool or as a therapeutic target. Potential markers include microRNAs (miRNAs), which are short, low molecular weight RNAs 19-24 nt long that regulate genes associated with cell proliferation, differentiation, and development in various cancers. In this study, we investigated the molecular mechanisms by which miR-145...

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PMID: 26514209
DOI: 10.1186/s12885-015-1846-0

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