Article
MiR-145 in cancer therapy resistance and sensitivity: A comprehensive review.
Cancer science - 1 Sept 2020
Xu Wenxiu, Hua Yuting, Deng Fei, Wang Dandan, Wu Yang, Zhang Wei, Tang Jinhai
Abstract excerpt
MircoRNA (miRNA) are a group of small, non-coding, regulatory RNA with an average length of approximately 22 nucleotides, which mostly modulate gene expression post-transcriptionally through complementary binding to the 3'-untranslated region (3'-UTR) of multiple target genes. Emerging evidence has shown that miRNA are frequently dysregulated in a variety of human malignancies. Among them, microRNA-145 (miR-145)...
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