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Article

MiR-145 inhibits cell proliferation of human lung adenocarcinoma by targeting EGFR and NUDT1.

RNA biology - 1 Jan 2000

Cho William C S, Chow Andrew S C, Au Joseph S K

Abstract excerpt

MicroRNAs (miRNAs) are emerging as important modulators in cellular pathways and they appear to play a key role in tumorigenesis. MiR-145 is downregulated in several human malignancies, including lung cancer, but the responsible molecular mechanisms remain unclear. We previously reported that restoration of hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor...

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Share to Adenocarcinoma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21289483
DOI: 10.4161/rna.8.1.14259

Genes

EGFR
NUDT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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