Article
Quantifying the impact of human immunodeficiency virus-1 escape from cytotoxic T-lymphocytes.
PLoS computational biology - 4 Nov 2010
Kadolsky Ulrich D, Asquith Becca
Abstract excerpt
HIV-1 escape from the cytotoxic T-lymphocyte (CTL) response leads to a weakening of viral control and is likely to be detrimental to the patient. To date, the impact of escape on viral load and CD4(+) T cell count has not been quantified, primarily because of sparse longitudinal data and the diff...
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