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Article

klf2ash317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes.

PloS one - 1 Jan 2015

Novodvorsky Peter, Watson Oliver, Gray Caroline, Wilkinson Robert N, Reeve Scott, Smythe Carl, Beniston Richard, Plant Karen, Maguire Richard, M K Rothman Alexander, Elworthy Stone, van Eeden Fredericus J M, Chico Timothy J A

Abstract excerpt

INTRODUCTION AND OBJECTIVES: The zinc-finger transcription factor Krϋppel-like factor 2 (KLF2) transduces blood flow into molecular signals responsible for a wide range of responses within the vasculature. KLF2 maintains a healthy, quiescent endothelial phenotype. Previous studies report a range of phenotypes following morpholino antisense oligonucleotide-induced klf2a knockdown in zebrafish. Targeted genome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26506092
DOI: 10.1371/journal.pone.0141611
PMCID: PMC4624238

Genes

KLF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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