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Article

Syndecan-2 is essential for angiogenic sprouting during zebrafish development.

Blood - 1 Mar 2004

Chen Eleanor, Hermanson Spencer, Ekker Stephen C

Abstract excerpt

We used a morpholino-based gene-targeting screen to identify a novel protein essential for vascular development using the zebrafish, Danio rerio. We show that syndecan-2, a cell-surface heparan sulfate proteoglycan, is essential for angiogenic sprouting during embryogenesis. The vascular function of syndecan-2 is likely conserved, as zebrafish and mouse syndecan-2 show similar expression patterns around major...

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Source

Identifiers

PMID: 14592839
DOI: 10.1182/blood-2003-06-1783

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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