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Article

Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis.

Current biology : CB - 20 Aug 2002

Habeck Hinrich, Odenthal Jörg, Walderich Brigitte, Maischein Hans, Schulte-Merker Stefan

Abstract excerpt

Blood vessels form either by the assembly and differentiation of mesodermal precursor cells (vasculogenesis) or by sprouting from preexisting vessels (angiogenesis). Endothelial-specific receptor tyrosine kinases and their ligands are known to be essential for these processes. Targeted disruption of vascular endothelial growth factor (VEGF) or its receptor kdr (flk1, VEGFR2) in mouse embryos results in a severe...

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Source

Identifiers

PMID: 12194822
DOI: 10.1016/s0960-9822(02)01044-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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