Article
Predicting cirrhosis and clinical outcomes in patients with advanced chronic hepatitis C with a panel of genetic markers (CRS7).
Pharmacogenetics and genomics - 1 Dec 2011
Curto Teresa M, Lagier Robert J, Lok Anna S, Everhart James E, Rowland Charles M, Sninsky John J
Abstract excerpt
OBJECTIVES: Genetic factors may play a role in fibrosis progression in patients with chronic hepatitis C (CHC). A cirrhosis risk score (CRS7) with seven single nucleotide polymorphisms was previously shown to correlate with cirrhosis in patients with CHC. This study aimed to assess the validity o...
Topics
- Antiviral Agents
- Carcinoma, Hepatocellular
- Cohort Studies
- Disease Progression
- Female
- Genetic Markers
- Hepatitis C, Chronic
- Humans
- Interferon-alpha
- Liver Cirrhosis
- Liver Neoplasms
- Male
- Middle Aged
- Polyethylene Glycols
- Polymorphism, Single Nucleotide
