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Article

ALK gene alterations in cancer: biological aspects and therapeutic implications.

Pharmacogenomics - 1 Feb 2017

Palmirotta Raffaele, Quaresmini Davide, Lovero Domenica, Silvestris Franco

Abstract excerpt

ALK was first reported in 1994 as a translocation in anaplastic large cell lymphoma and then described with different abnormalities in a number of tumors. Recently, a shortly accumulated biomedical research clarified the numerous biological processes underlying its ability to support cancer development, growth and progression. Advent of precision medicine has finally provided unexpected advances, leading to the...

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Source

Identifiers

PMID: 28112990
DOI: 10.2217/pgs-2016-0166

Genes

ALK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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ALK gene alterations in cancer: biological aspects and therapeutic implications.PMID 28112990Read ↗

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