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Article

Anaplastic lymphoma kinase: Role in cancer and therapy perspective.

Cancer biology & therapy - 1 Jan 2015

Zhao Zhihong, Verma Vivek, Zhang Mutian

Abstract excerpt

Anaplastic lymphoma kinase (ALK) is correlated with oncogenesis in different types of cancers, such as anaplastic large cell lymphoma, lung cancer, neuroblastoma, and even breast cancer, by abnormal fusion of ALK or non-fusion ALK activation. ALK is a receptor tyrosine kinase, with a single transmembrane domain, that plays an important role in development. Upon ligand binding to the extracellular domain, the...

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Source

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Identifiers

PMID: 26529396
DOI: 10.1080/15384047.2015.1095407
PMCID: PMC4847817

Genes

ALK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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