Article

Comprehensive genomic analysis reveals molecular heterogeneity in pediatric ALK-positive anaplastic large cell lymphoma

2024-03-28

Abstract excerpt

<title>Abstract</title> <p>Anaplastic large cell lymphoma (ALCL) is a mature T-cell lymphoma that accounts for for 10–15% of childhood lymphomas. Despite the observation that more than 90% of pediatric cases harbor the anaplastic lymphoma kinase (ALK) rearrangement resulting in aberrant ALK kinase expression, there is significant clinical, morphologic, and biological heterogeneity. To gain insights into the genom...

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Literature Corpus work: d33d4b77-4e3e-5cb6-a96a-a8bee35d2895
DOI: 10.21203/rs.3.rs-4145750/v1

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