SF3A1 and pancreatic cancer: new evidence for the association of the spliceosome and cancer.

doi:10.18632/oncotarget.5647

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Article

SF3A1 and pancreatic cancer: new evidence for the association of the spliceosome and cancer.

Oncotarget - 10 Nov 2015

Tian Jing, Liu Yaping, Zhu Beibei, Tian Yao, Zhong Rong, Chen Wei, Lu Xinghua, Zou Li, Shen Na, Qian Jiaming, Li Hui, Miao Xiaoping, Wang Li

Abstract excerpt

A two-stage case-control study was conducted to examine the association between six candidate U2-depedent spliceosome genes (SRSF1, SRSF2, SF3A1, SF3B1, SF1 and PRPF40B) and pancreatic cancer (PC). Subjects with one or two T alleles at rs2074733 in SF3A1 had a lower risk of PC compared to those with two C alleles in combined two populations (OR: 0.59, 95% confidence interval: 0.48-0.73, False discovery rate...

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Identifiers

PMID: 26498691
DOI: 10.18632/oncotarget.5647
PMCID: PMC4741962

Genes

SRSF1
SRSF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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