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Article

A single nucleotide polymorphism in the 3'-UTR of STAT3 regulates its expression and reduces risk of pancreatic cancer in a Chinese population.

Oncotarget - 20 Sept 2016

Zhu Beibei, Zhu Ying, Lou Jiao, Ke Juntao, Zhang Yi, Li Jiaoyuan, Gong Yajie, Yang Yang, Tian Jianbo, Peng Xiating, Zou Danyi, Zhong Rong, Gong Jing, Chang Jiang, Li Lu, Miao Xiaoping

Abstract excerpt

Pancreatic cancer (PC) is one of the deadliest solid malignancies carrying a gloomy 5-year survival rate less than 5%. The signal transducer and activator of transcription 3 (STAT3) is a common transcriptional regulator, whose aberrant expression has been widely found in human cancers, including PC. Our current study aimed to illustrate the roles of common variants, in the three prime untranslated region (3'UTR)...

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Identifiers

PMID: 27577070
DOI: 10.18632/oncotarget.11607
PMCID: PMC5308728

Genes

STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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