Article
Studying the connection between SF3B1 and four types of cancer by analyzing networks constructed based on published research.
Scientific reports - 15 Feb 2023
Samy Asmaa, Ozdemir Mehmet Kemal, Alhajj Reda
Abstract excerpt
Splicing factor 3B subunit 1 (SF3B1) is the largest component of SF3b protein complex which is involved in the pre-mRNA splicing mechanism. Somatic mutations of SF3B1 were shown to be associated with aberrant splicing, producing abnormal transcripts that drive cancer development and/or prognosis. In this study, we focus on the relationship between SF3B1 and four types of cancer, namely myelodysplastic syndrome...
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