Article
The Role of Splicing Factor SF3B4 in Congenital Diseases and Tumors.
Discovery medicine - 1 Jan 2000
Yan Li, Yang Xingwen, Yang Xiaoyan, Yuan Xiumei, Wei Lianhua, Si Yuchun, Li Dehong
Abstract excerpt
In eukaryotes, spliceosomes catalyze the splicing of pre-mRNA to mature mRNA. As the core subunit of U2 spliceosome, splicing factor SF3b4 plays not only a crucial role in the splicing process, but also a role in transcription, translation, and cell signal transduction, and participates in the regulation of cell cycle, cell differentiation, and immune deficiency. In recent years, more and more research studies on...
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