Article
Structure of the yeast nucleosome core particle reveals fundamental changes in internucleosome interactions.
The EMBO journal - 17 Sept 2001
White C L, Suto R K, Luger K
Abstract excerpt
Chromatin is composed of nucleosomes, the universally repeating protein-DNA complex in eukaryotic cells. The crystal structure of the nucleosome core particle from Saccharomyces cerevisiae reveals that the structure and function of this fundamental complex is conserved between single-cell organisms and metazoans. Our results show that yeast nucleosomes are likely to be subtly destabilized as compared with...
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