Article
Whole genome SNP genotype piecemeal imputation.
BMC bioinformatics - 23 Oct 2015
Wang Yining, Wylie Tim, Stothard Paul, Lin Guohui
Abstract excerpt
BACKGROUND: Despite ongoing reductions in the cost of sequencing technologies, whole genome SNP genotype imputation is often used as an alternative for obtaining abundant SNP genotypes for genome wide association studies. Several existing genotype imputation methods can be efficient for this purpose, while achieving various levels of imputation accuracy. Recent empirical results have shown that the two-step...
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