Article
Genotype imputation.
Annual review of genomics and human genetics - 1 Jan 2009
Li Yun, Willer Cristen, Sanna Serena, Abecasis Gonçalo
Abstract excerpt
Genotype imputation is now an essential tool in the analysis of genome-wide association scans. This technique allows geneticists to accurately evaluate the evidence for association at genetic markers that are not directly genotyped. Genotype imputation is particularly useful for combining results across studies that rely on different genotyping platforms but also increases the power of individual scans. Here, we...
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