Article
A joint use of pooling and imputation for genotyping SNPs.
BMC bioinformatics - 13 Oct 2022
Clouard Camille, Ausmees Kristiina, Nettelblad Carl
Abstract excerpt
BACKGROUND: Despite continuing technological advances, the cost for large-scale genotyping of a high number of samples can be prohibitive. The purpose of this study is to design a cost-saving strategy for SNP genotyping. We suggest making use of pooling, a group testing technique, to drop the amount of SNP arrays needed. We believe that this will be of the greatest importance for non-model organisms with more...
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