Article
Genotyping, the Usefulness of Imputation to Increase SNP Density, and Imputation Methods and Tools.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2022
Phocas Florence
Abstract excerpt
Imputation has become a standard practice in modern genetic research to increase genome coverage and improve accuracy of genomic selection and genome-wide association study as a large number of samples can be genotyped at lower density (and lower cost) and, imputed up to denser marker panels or to sequence level, using information from a limited reference population. Most genotype imputation algorithms use...
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